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个人信息

博士生导师
研究员

2022年获得“国家杰出青年基金”


Email: szhan@cemps.ac.cn
个人网页:

研究方向

昆虫适应性进化

詹帅

个人简介

2001年9月-2005年6月 南京大学 本科
2005年9月-2010年7月 中国科学院上海植物生理生态研究所 硕博连读
2010年9月-2014年2月 美国马萨诸塞大学医学院 博士后
2014年3月-至今 中国科学院上海植物生理生态研究所/分子植物科学卓越创新中心研究员/研究组长
先后承担基金委优秀青年科学基金、杰出青年科学基金、重点项目、重大研究计划等；获中国科协第十六届中国青年科技奖、中国昆虫学会第七届青年科学技术奖、中国科学院朱李月华优秀教师奖等；担任中国昆虫学会理事、上海市昆虫学会副理事长等，获上海市科技系统优秀共产党员等称号；入选全球前2%顶尖科学家榜单，论文总引用超4000次。

研究工作

主要从事昆虫适应性进化研究，代表性研究成果发表在Science、Nature、Cell、Nature Ecology & Evolution、Cell Genomics、Science Advances、Nature Communication、Cell Reports、Cell Research、National Science Review等国际学术期刊。

（1）昆虫季节性适应：解析昆虫季节性适应行为（迁飞、滞育等）调控的遗传基础和演化规律，探究昆虫种群对纬度、光周期、温度等环境因子的适应机制。

（2）昆虫食性演化：重点关注植食性昆虫对寄主的选择与适应机制，包括多食性与单食性昆虫的分化机制、近缘种间食性分化的演化机制、远缘物种间食性趋同的演化机制等。

（3）昆虫大数据与人工智能：基于跨物种、多组学数据挖掘昆虫性状多样性形成的组学规律，基于AI设计分子用于害虫防治和益虫利用。

主要成果

    1.Liu Y,Pan Y,Cao Y,Wang Z,Ge C,…,Fang G,Wang Y*,Xiao Q*,Zhan S* (2025) The genetics and evolution of moth melanism in the absence of strong natural selection. National Science Review nwaf441.

    2.Huang J*,Chen X,Zhan S (2025) Molecular Mechanisms Underlying Parasitoid-Derived Host Manipulation Strategies. Annual Review of Entomology annurev-ento-121423-013603.

    3.Cui Y,Fang G,Zhong J,Bai X,Xue H,…,Wang W,Liu Y*,Zhan S*,Xiang H* (2025) Divergent and convergent evolution underlie the cocoon-spinning diversity. The Innovation Life 3:100144.

    4.Dong Z,Lu Y,Fang G,Zhang Q,Sheng Y,…,Li G,Chen X,Huang J*,Zhan S* (2025) A rare,evolutionarily conserved venom protein benefits endoparasitism across parasitoids. Cell Genomics 5:100920.

    5.Zheng S,Wang Y,Li G,Qin S,Dong Z,Yang X,Xu X,Fang G,Li M,Zhan S* (2025) Functional polymorphism of CYCLE underlies the diapause variation in moths. Science 388:eado2129.

    6.Xu J,Lei Y,Zhang X,Li J,Lin Q,…,Hu YH,Zhan S,Gao C*,Chen XY* (2025) Design of CoQ10 crops based on evolutionary history. Cell 188:1941-1954.e15.

    7.Wu J,Li G,Lin Z,Zhang Y,Yu W,Hu R,Zhan S*,Chen Y* (2025) A chromosome-level genome assembly of the cabbage aphid Brevicoryne brassicae. Scientific Data 12:167.

    8.Pang L,Fang G,Liu Z,Dong Z,Chen J,….,Li G,Chen X,Zhan S*,Huang J* (2024) Coordinated molecular and ecological adaptations underlie a highly successful parasitoid. eLife 13:RP94748.

    9.Hu Q,Zhuo J,Fang G,Lu J,Ye Y,…,Li JM,Chen J,Zhan S*,Zhang CX* (2024) The genomic history and global migration of a windborne pest. Science Advances 10:eadk3852.

    10.Tong D,Zhang L,Wu N,Xie D,Fang G,….,Cheng Y,Xia J,Jiang X*,Zhan S* (2022) The oriental armyworm genome yields insights into the long-distance migration of noctuid moths. Cell Reports 41:111843.

    11.Wang Y,Fang G,Xu P,Gao B,Liu X,…,Pereira R,Huang Y,Niu C*,Zhan S* (2022) Behavioral and genomic divergence between a generalist and a specialist fly. Cell Reports 41:111654.

    12.Wang Y,Fang G,Chen X,Cao Y,Wu N,Cui Q,Zhu C,Qian L,Huang Y*,Zhan S* (2021) The genome of the black cutworm Agrotis ipsilon. Insect Biochem Mol Biol 139:103665.

    13.Fang G,Zhang Q,Chen X,Cao Y,Wang Y,Qi M,Wu N,Qian L,Zhu C,Huang Y*,Zhan S* (2021) The draft genome of the Asian corn borer yields insights into ecological adaptation of a devastating maize pest. Insect Biochem Mol Biol 138:103638.

    14.Chen J,Fang G,Pang L,Sheng Y,Zhang Q,….,Shi M,Chen X*,Zhan S*,Huang J* (2021) Neofunctionalization of an ancient domain allows parasites to avoid intraspecific competition by manipulating host behaviour. Nature Communications 12:5489.

    15.Pan Y,Fang G,Wang Z,Cao Y,Liu Y,Li G,Liu X,Xiao Q*,Zhan S* (2021) Chromosome-level genome reference and genome editing of the tea geometrid. Molecular Ecology Resources 21:2034-2049.

    16.Huang J*,Chen J,Fang G,Pang L,Zhou S,….,Li G,Shi M,Chen X*,Zhan S* (2021) Two novel venom proteins underlie divergent parasitic strategies between a generalist and a specialist parasite. Nature Communications 12: 234.

    17.Mei L,Chen M,Shang Y,Tang G,Tao Y,Zeng L,Huang B,Li Z,Zhan S*,Wang C* (2020) Population genomics and evolution of a fungal pathogen after releasing exotic strains to control insect pests for 20 years. The ISME Journal 14:1422-1434.

    18.Liu A,Chen W,Huang C,Qian C,Liang Y,Li S*,Zhan S*,Luan Y* (2020) MicroRNA evolution provides new evidence for a close relationship of Diplura to Insecta. Systematic Entomology 45: 365–377.

    19.Zhan S*,Fang G,Cai M,Kou Z,Xu J,…,Wang S,Tomberlin JK*,Zhang J*,Huang Y* (2020) Genomic landscape and genetic manipulation of the black soldier fly Hermetia illucens,a natural waste recycler. Cell Research 30: 50-60.

    20.Wang Y,Chen X,Yang Y,Xu J,Fang G,Niu C,Huang Y,Zhan S* (2019) The Masc gene product controls masculinization in the black cutworm,Agrotis ipsilon. Insect Science 26:1037-1044.

    21.Zhang T,Yuan D,Xie J,Lei Y,Li J,…,Zhang J,Zhu M,Zhan S*,Li S* (2019) Evolution of the cholesterol biosynthesis pathway in animals. Molecular Biology and Evolution 36: 2548–2556.

    22.Quan Q,Hu X,Pan B,Zeng B,Wu N,…,Chen X,Li X,Huang Y*,Zhan S* (2019) Draft genome of the cotton aphid Aphis gossypii. Insect Biochem Mol Biol 105:25-32.

    23.Qiu C,Zhang Y,Fan YJ,Pang TL,Su Y,Zhan S*,Xu Y* (2019) HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila. J Mol Cell Biol 11:170-181.

    24.Wu N,Zhang S,Li X,Cao Y,Liu X,….,James A ,Zhang Z*,Huang Y*,Zhan S* (2019) Fall webworm genomes yield insights into rapid adaptation of invasive species. Nature Ecology & Evolution 3:105-115.

    25.Xiang H,Liu X,Li M,Zhu Y,Wang L,Cui Y,Liu L,Fang G,Qian H,Xu A*,Wang W*,Zhan S* (2018) The evolutionary road from wild moth to domestic silkworm. Nature Ecology & Evolution 2:1268-1279.

    26.Li S*,Zhu S,Jia Q,Yuan D,Ren C,…,Fan Y,Yu X,Feng Q,Zhan S* (2018) The genomic and functional landscapes of developmental plasticity in the American cockroach. Nature Communications 9:1008.

    27.Zhan S*,Zhang W,Niitepõld K,Hsu J,Haeger F,Zalucki MP,Altizer S,de Roode JC,Reppert SM,Kronforst MR* (2014) The genetics of monarch butterfly migration and warning coloration. Nature 514:317-321.

    28.Zhan S,Reppert SM* (2013) MonarchBase: the monarch butterfly genome database. Nucleic Acids Research 41:D758-D763.

    29.Zhan S,Merlin C,Boore JL and Reppert SM* (2011) The monarch butterfly genome yields insights into long-distance migration. Cell 147:1171-1185.

    30.Zhan S,Guo Q,Li M,Li M,Li J,Miao X,Huang Y* (2010) Disruption of an N-acetyltransferase gene in the silkworm reveals a novel role in pigmentation. Development 137: 4083-4090.